Parafascicular thalamic nucleus activity in a rat model of Parkinson's disease
نویسندگان
چکیده
منابع مشابه
Neurobiology of Disease Involvement of the Thalamic Parafascicular Nucleus in Mesial Temporal Lobe Epilepsy
Mélanie Langlois,1 Pierre-Olivier Polack,3 Hélène Bernard,1 Olivier David,2 Stéphane Charpier,3 Antoine Depaulis,1 and Colin Deransart1 1Equipe 9, Dynamique des Réseaux Synchrones Epileptiques, and 2Equipe 5, Neuroimagerie Fonctionnelle et Métabolique, Grenoble Institut des Neurosciences, Institut National de la Santé et de la Recherche Médicale U 836-Université Joseph Fourier-Commisariat à l’E...
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The present study investigated the effects of microinjections of acetylcholine (a cholinergic agonist), physostigmine (a cholinesterase inhibitor), atropine (an antagonist of muscarinic cholinergic receptors) and hexamethonium (an antagonist of nicotinic cholinergic receptors) into the parafascicular nucleus of thalamus on the acute corneal nociception in rats. Acute corneal nociception was ind...
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23 The parafascicular nucleus (Pf) receives cholinergic input from the pedunculopontine 24 nucleus, part of the reticular activating system involved in waking and REM sleep, and sends 25 projections to the cortex. We tested the hypothesis that Pf neurons fire maximally at gamma 26 band frequency (30-90 Hz), that this mechanism involves high threshold voltage-dependent 27 P/Qand N-type calcium c...
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The lateral parafascicular nucleus (lPf) is a member of the intralaminar thalamic nuclei, a collection of nuclei that characteristically provides widespread projections to the neocortex and basal ganglia and is associated with arousal, sensory, and motor functions. Recently, lPf neurons have been shown to possess different characteristics than other cortical-projecting thalamic relay neurons. W...
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The parafascicular nucleus (PFN) of thalamus, as a supraspinal structure, has an important role in processing of nociceptive information. In addition, μ-opioid receptor contributes to supraspinal modulation of nociception. In the present study, the effects of microinjection of naloxone (a non-specific opioid-receptor antagonist) and naloxonazine (a specific μ-opioid receptor antagonist) were in...
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ژورنال
عنوان ژورنال: Experimental Neurology
سال: 2009
ISSN: 0014-4886
DOI: 10.1016/j.expneurol.2009.02.010